Biology (Grades 9–10) Midterm — Semester 2, Form A
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Free printable Biology midterm (Grades 9–10): 15 multiple-choice questions plus 1 written response covering Cell Division & DNA, Genetics, Evolution & Ecology. Answer key included — customize it in the Midterm Maker.
Biology (Grades 9–10) Midterm — Semester 2, Form A
Name: Date: Period:
Directions: Read each question carefully and choose the best answer. Answer the written response in complete sentences.
Covers: Cell Division & DNA · Genetics · Evolution & Ecology
Part 1: Multiple Choice
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In a sample of double-stranded DNA, 30% of the bases are adenine. What percent are guanine?
- A. 40%
- B. 20%
- C. 30%
- D. 70%
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Meiosis produces what?
- A. Four genetically different haploid cells
- B. Two identical diploid cells
- C. Four identical diploid cells
- D. Two different haploid cells
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One DNA strand reads ATCGGA. What is the complementary DNA strand?
- A. GCTAAG
- B. UAGCCU
- C. ATCGGA
- D. TAGCCT
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In RNA, which base replaces thymine?
- A. Uracil
- B. Guanine
- C. Cytosine
- D. Adenine
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Crossing over, which increases genetic variation, occurs during which stage?
- A. S phase of interphase
- B. Anaphase of mitosis
- C. Telophase II of meiosis
- D. Prophase I of meiosis
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In a cross of AaBb × AaBb, what fraction of offspring are expected to be aabb?
- A. 1/8
- B. 3/16
- C. 1/4
- D. 1/16
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A carrier mother (XᴴXʰ) and an unaffected father (XᴴY) have a son. What is the probability the son has hemophilia?
- A. 0%
- B. 25%
- C. 50%
- D. 100%
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Red and white snapdragons are crossed and all offspring are pink. What inheritance pattern is this?
- A. Complete dominance
- B. Codominance
- C. Incomplete dominance
- D. Sex-linked inheritance
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What phenotypic ratio is expected from a dihybrid cross of AaBb × AaBb with independent assortment?
- A. 3:1
- B. 1:1:1:1
- C. 1:2:1
- D. 9:3:3:1
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A person with type AB blood has A antigens and B antigens on their red blood cells. What inheritance pattern is this?
- A. Sex-linked inheritance
- B. Polygenic inheritance
- C. Incomplete dominance
- D. Codominance
-
Primary succession begins in which type of area?
- A. An area with no soil, such as new lava rock
- B. An abandoned farm field
- C. A mowed lawn
- D. A forest after a wildfire
-
Producers in an ecosystem contain 10,000 kcal. Using the 10% rule, about how much energy reaches secondary consumers?
- A. 5,000 kcal
- B. 10 kcal
- C. 100 kcal
- D. 1,000 kcal
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Which condition is required for natural selection to occur?
- A. A population of identical individuals
- B. Unlimited food and space
- C. Individuals changing traits on purpose
- D. Inherited variation among individuals
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Which organisms convert nitrogen gas from the air into forms plants can use?
- A. Green plants
- B. Viruses
- C. Nitrogen-fixing bacteria
- D. Herbivores
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Random changes in allele frequencies that have the greatest effect in small populations are called what?
- A. Natural selection
- B. Artificial selection
- C. Genetic drift
- D. Gene flow
Part 2: Written Response
- Compare mitosis and meiosis. Explain why meiosis is necessary for sexual reproduction and how it increases genetic variation.
Answer Key — Biology (Grades 9–10) Midterm — Semester 2, Form A
- B — 20% A = T = 30%, leaving 40% split equally: G = C = 20%.
- A — Four genetically different haploid cells Meiosis has two divisions and creates variation.
- D — TAGCCT A pairs with T and C pairs with G.
- A — Uracil RNA uses uracil, which pairs with adenine.
- D — Prophase I of meiosis Homologous chromosomes exchange segments in prophase I.
- D — 1/16 1/4 aa × 1/4 bb = 1/16.
- C — 50% Sons get the father's Y, and half get the mother's Xʰ.
- C — Incomplete dominance Neither allele fully masks the other, producing a blend.
- D — 9:3:3:1 Independent genes each give 3:1, combining to 9:3:3:1.
- D — Codominance Both alleles are fully expressed at the same time.
- A — An area with no soil, such as new lava rock Primary succession starts where no soil exists; pioneer species begin it.
- C — 100 kcal 10,000 → 1,000 (primary) → 100 (secondary).
- D — Inherited variation among individuals Selection acts on heritable differences in survival and reproduction.
- C — Nitrogen-fixing bacteria Bacteria in soil and root nodules convert N₂ into ammonia.
- C — Genetic drift Chance events shift allele frequencies most in small populations.
Written Response — Look-Fors
- Mitosis: one division, 2 identical diploid cells, growth/repair; meiosis: two divisions, 4 different haploid gametes; keeps chromosome number constant after fertilization; crossing over and independent assortment create variation.